Description
🐶 Zycortal Suspension 25 mg | Mineralocorticoid Therapy for Dogs with Addison’s Disease
Zycortal Suspension 25 mg/ml is a veterinary injectable medication used as replacement therapy for mineralocorticoid deficiency in dogs diagnosed with primary hypoadrenocorticism, commonly known as Addison’s disease. It contains desoxycorticosterone pivalate, a synthetic hormone that mimics the action of aldosterone — helping regulate sodium, potassium, and fluid balance in the body.
💉 Key Features
- Active Ingredient: Desoxycorticosterone pivalate
- Concentration: 25 mg/ml
- Form: Aqueous injectable suspension
- Use: Subcutaneous injection only, prescribed by a licensed veterinarian
🧬 How It Works
Zycortal helps restore electrolyte balance by:
- Retaining sodium and chloride in the kidneys
- Excreting potassium and hydrogen ions
- Promoting water absorption to maintain blood pressure and hydration
- Supporting cardiac output and tissue perfusion
This makes it essential for dogs with Addison’s disease, whose adrenal glands fail to produce enough mineralocorticoids.
📋 Dosage & Administration
- Initial dose: 2.2 mg/kg body weight via subcutaneous injection
- Monitoring: Sodium/potassium ratio checked at Day 10 and Day 25
- Adjustments: Dose and interval tailored based on clinical response and lab results
- Often used alongside glucocorticoids like prednisone or prednisolone for full adrenal support
⚠️ Precautions & Side Effects
- Not for use in dogs with heart disease, renal failure, or hepatic issues without veterinary supervision
- Common side effects: polyuria, polydipsia, lethargy, vomiting, diarrhea, and weight gain
- Avoid use in pregnant dogs
- Must be stored properly and shaken before use
Zycortal Suspension is a long-term management solution for dogs with Addison’s disease, offering reliable control of symptoms and improved quality of life. Always consult your veterinarian for proper diagnosis, dosage, and monitoring.
